Mosquito hemocyte-mediated immune responses
نویسندگان
چکیده
منابع مشابه
Comprehensive Genetic Dissection of the Hemocyte Immune Response in the Malaria Mosquito Anopheles gambiae
Reverse genetics in the mosquito Anopheles gambiae by RNAi mediated gene silencing has led in recent years to an advanced understanding of the mosquito immune response against infections with bacteria and malaria parasites. We developed RNAi screens in An. gambiae hemocyte-like cells using a library of double-stranded RNAs targeting 109 genes expressed highly or specifically in mosquito hemocyt...
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The lack of genetic means has been a serious limitation in studying mosquito immunity. We generated Relish-mediated immune deficiency (RMID) by transforming Aedes aegypti with the Delta Rel transgene driven by the vitellogenin (Vg) promoter using the pBac[3xP3-EGFP, afm] vector. A stable transformed line had a single copy of the Vg-Delta Rel transgene. The Vg-Delta Rel transgene expression was ...
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ژورنال
عنوان ژورنال: Current Opinion in Insect Science
سال: 2014
ISSN: 2214-5745
DOI: 10.1016/j.cois.2014.07.002